TY - BOOK AU - Ramanathan,Ragu TI - Mass spectrometry in drug metabolism and pharmacokinetics SN - 9780471751588 (cloth) U1 - 615.7 22 PY - 2009/// CY - Hoboken, N.J. PB - Wiley KW - Drugs KW - Metabolism KW - Research KW - Methodology KW - Design KW - Mass spectrometry KW - Pharmacokinetics KW - Pharmaceutical Preparations KW - metabolism KW - Drug Design KW - Drug Evaluation, Preclinical KW - methods KW - Mass Spectrometry N1 - شراء معرض القاهرة للكتاب 2019 ; Includes bibliographical references and index; Evolving role of mass spectrometry in drug discovery and development / Dil M. Ramanathan and Richard M. LeLacheur -- Quantitative bioanalysis in drug discovery and development : principles and applications / Ayman El-Kattan, Chris Holliman, and Lucinda H. Cohen -- Quadrupole, triple-quadrupole, and hybrid linear ion trap mass spectrometers in metabolite analysis / Elliott B. Jones -- Applications of quadrupole time-of-flight mass spectrometry in reactive metabolite screening / Jose M. Castro-Perez -- Changing role of FTMS in drug metabolism / Petia A. Shipkova, Jonathan L. Josephs, and Mark Sanders -- High-resolution LC-MS based mass defect filter approach : basic concept and application in metabolite detection / Haiying Zhang ... [et al.]; Applications of high-sensitivity mass spectrometry and radioactivity detection techniques in drug metabolism studies / Wing W. Lam ... [et al.] -- Online electrochemical-LC-MS techniques for profiling and characterizing metabolites and degradants / Paul H. Gamache ... [et al.] -- LC-MS methods with hydrogen/deuterium exchange for identification of hydroxylamine, n-oxide, and hydroxylated analogs of desloratadine / Natalia A. Penner ... [et al.] -- Turbulent-flow LC-MS : applications for accelerating pharmacokinetic profiling and metabolite identification / Joseph L. Herman and Joseph M. Di Bussolo -- Desorption ionization techniques for quantitative analysis of drug molecules / Jason S. Gobey, John Janiszewski, and Mark J. Cole -- MALDI imaging mass spectrometry for direct tissue analysis of pharmaceuticals / Yunsheng Hsieh and Walter A. Korfmacher ER -