000			03481cam a22004694a 4500
999			_c26374 _d26373
001			15295836
003			SA-RiNAUS
005			20190414082550.0
008			080509s2009 njua b 001 0 eng d
020			_a9780471751588 (cloth)
040			_aDNLM/DLC _beng _cDLC _dNLM _dUKM _dBTCTA _dBAKER _dYDXCP _dC#P _dCDX _dIXA _dDEBBG _dOCLCQ _dOCL _dDLC
082	0	0	_222 _a615.7 _bM S M
245	0	0	_aMass spectrometry in drug metabolism and pharmacokinetics / _cedited by Ragu Ramanathan.
260			_aHoboken, N.J. : _bWiley, _cc2009.
300			_axii, 389 p. : _bill. ; _c25 cm.
500			_aشراء معرض القاهرة للكتاب 2019
504			_aIncludes bibliographical references and index.
505	0		_aEvolving role of mass spectrometry in drug discovery and development / Dil M. Ramanathan and Richard M. LeLacheur -- Quantitative bioanalysis in drug discovery and development : principles and applications / Ayman El-Kattan, Chris Holliman, and Lucinda H. Cohen -- Quadrupole, triple-quadrupole, and hybrid linear ion trap mass spectrometers in metabolite analysis / Elliott B. Jones -- Applications of quadrupole time-of-flight mass spectrometry in reactive metabolite screening / Jose M. Castro-Perez -- Changing role of FTMS in drug metabolism / Petia A. Shipkova, Jonathan L. Josephs, and Mark Sanders -- High-resolution LC-MS based mass defect filter approach : basic concept and application in metabolite detection / Haiying Zhang ... [et al.].
505	0		_aApplications of high-sensitivity mass spectrometry and radioactivity detection techniques in drug metabolism studies / Wing W. Lam ... [et al.] -- Online electrochemical-LC-MS techniques for profiling and characterizing metabolites and degradants / Paul H. Gamache ... [et al.] -- LC-MS methods with hydrogen/deuterium exchange for identification of hydroxylamine, n-oxide, and hydroxylated analogs of desloratadine / Natalia A. Penner ... [et al.] -- Turbulent-flow LC-MS : applications for accelerating pharmacokinetic profiling and metabolite identification / Joseph L. Herman and Joseph M. Di Bussolo -- Desorption ionization techniques for quantitative analysis of drug molecules / Jason S. Gobey, John Janiszewski, and Mark J. Cole -- MALDI imaging mass spectrometry for direct tissue analysis of pharmaceuticals / Yunsheng Hsieh and Walter A. Korfmacher.
650		0	_aDrugs _xMetabolism _xResearch _xMethodology. _92311
650		0	_aDrugs _xDesign. _92311
650		0	_aMass spectrometry. _92314
650		0	_aPharmacokinetics _xResearch _xMethodology. _92343
650	1	2	_aPharmaceutical Preparations _xmetabolism. _92189
650	2	2	_aDrug Design. _92344
650	2	2	_aDrug Evaluation, Preclinical _xmethods. _92345
650	2	2	_aMass Spectrometry _xmethods. _92314
650	2	2	_aPharmacokinetics. _92346
700	1		_aRamanathan, Ragu. _92347
942			_2ddc _cBK