000 01930cam a22003011i 4500
003 SA-RiNAUS
005 20220322095410.0
008 160928t2021 xxk f bi 000 0 eng
020 _a9781009045810
040 _aSA-RiNAUS
_bara
_cSA-RiNAUS
_erda
082 _221
_a572.86
_bV A B
100 1 _a Vologodskii, Alexander
_eauther .
_930376
245 1 0 _a Biophysics of DNA /
_cAlexander Vologodskii.
264 1 _aUnited Kingdom :
_bUniversity of Cambridge,
_c[2021]
_m[1442]
264 1 _a©2021
300 _a254 pages ;
_c24 × 16 cm
500 _aIncludes index.
504 _aIncludes bibliographical references.
520 3 _aSurveying the last sixty years of research, this book describes the physical properties of DNA in the context of its biological functioning. It is designed to enable both students and researchers of molecular biology, biochemistry and physics to better understand the biophysics of DNA, addressing key questions and facilitating further research. The chapters integrate theoretical and experimental approaches, emphasising throughout the importance of a quantitative knowledge of physical properties in building and analysing models of DNA functioning. For example, the book shows how the relationship between DNA mechanical properties and the sequence specificity of DNA-protein binding can be analyzed quantitatively by using our current knowledge of the physical and structural properties of DNA. Theoretical models and experimental methods in the field are critically considered to enable the reader to engage effectively with the current scientific literature on the physical properties of DNA.
650 0 _a DNA-drug interactions.
_930377
650 0 _aAntibiotics.
_930370
650 0 _aActinomycin.
_930371
650 0 _aDNA
_x Structure.
_930378
650 0 _aDNA
_xConformation.
_930373
650 0 _aBiophysics.
_930374
942 _2ddc
_cBK
999 _c32504
_d32503